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**PLOS Biology** @PLOSBiology@fediscience.org · 27 gen

PLOS Biology @PLOSBiology@fediscience.org

Human #papillomavirus (HPV) infections drive 1 in 20 new cancer cases, mainly in women. Kinetic analysis of longitudinal clinical data reveals that #HPV infections exhibit a long-plateau #virus load, with clearance associated with host immune response signals #plosbiology plos.io/4aQgmo9

Left: This diagram represents variations in the mean number of viruses per cell in the samples over time. The dark band shows the median trajectory estimated by the model, and light bands are the 10% and 90% deciles. The thin lines correspond to the measured individual trajectory of the 164 infections detected in the participants of the PAPCLEAR cohort. Right: Clustering of immune cell populations labelled in 186 cervical smears from 73 HPV infected women. Each dot corresponds to one cell analysed by flow cytometry. The labels indicate the most likely type of cell population (granulocytes, CD8 T cells, CD16+ TCR-γδ cells, NK cells, monocytes, CD45low TCR-γδ cells, CD T cells).

**ETE** @ete@mamot.fr · 22 gen

22 gen

ETE @ete@mamot.fr

Si vous êtes intéressé-e par la #virologie, l'#immunologie ou les analyses #statistiques, l'article détaillé sur la dynamique des infections à #papillomavirus chez les jeunes femmes est disponible en #OpenAccess chez @PLOSBiology

https://doi.org/10.1371/journal.pbio.3002949

doi.orgViral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolutionHuman papillomavirus (HPV) infections drive one in twenty new cancer cases, with a particular burden on women. This analysis of longitudinal clinical data using kinetics models reveals that HPV infections exhibit a long plateau virus load and that their clearance is associated with specific signals in the host immune response.

**Scienza et Magia** @scienzamagia · 4 set 2023

4 set 2023

Scienza et Magia @scienzamagia

Oggi giornata mondiale informativa sulla salute sessuale. Hiv e non solo, in 10 anni infezioni sessuali in aumento. Colpiti i giovani, spesso senza diagnosi. Il 4 settembre giornata mondiale. La salute sessuale è un diritto che va garantito durante tutta la vita, dall'adolescenza e alla terza età.

#condilomi #Consent #giornatamondiale #Hiv #infezionisessuali #IstitutoSuperiorediSanità #Papillomavirus #Sifilide #Unfpa

https://scienzamagia.eu/sociale-collettivita/oggi-giornata-mondiale-informativa-sulla-salute-sessuale/

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